Here are all the WRs taken within the 100th pick for the last 4 drafts.
Give me your Top 10 based on their overall success since selection and then list your "MUST HAVE" Top 2 (knowing what you know now; if you knew then):
2023 WR Picks
JSN (20th)
Quentin Johnston (21) Zay Flowers (22) Jordan Addison (23) Jonathan Mingo (39) Jayden Reed (50) Rashee Rice (55) Marvin Mims (63) Tank Dell (69) Jalin Hyatt (73) Cedric Tillman (74) Josh Downs (80) Michael Wilson (94) Derius Davis (100)
2022 WR Picks
Drake London (8)
Garrett Wilson (10) Chris Olave (11) Jameson Williams (12) Jahan Dotson (16) Treylon Burks (18) Christian Watson (34) Wan'Dale Robinson (43) John Metchie III (44) Tyquan Thorton (50) George Pickens (52) Alec Pierce (53) Skyy Moore (54) Velus Jones (71) Jalen Tolbert (88) David Bell (99)
2021 WR Picks
Ja'Marr Chase (5) Jaylen Waddle (6) DeVonta Smith (10) Kadarious Toney (20) Rashod Bateman (27) Elijah Moore (34) Rondale Moore (49) D'Wayne Eskridge (56) Tutu Atwell (57) Terrace Marshall (59) Josh Palmer (77) Dyami Brown (82) Amari Rodgers (85) Nico Collins (89) Anthony Schwartz (91)
2020 WR Picks
Henry Ruggs (12)
Jerry Jeudy (15) CeeDee Lamb (17) Jalen Reagor (21) Justin Jefferson (22) Brandon Aiyuk (25) Tee Higgins (33) Michael Pittman Jr. (34) Laviska Shenault Jr. (42) KJ Hamler (46) Chase Claypool (49) Van Jefferson (57) Denzel Mims (59) Antonio Gibson (66) Bryan Edwards (81) Devin Duvernay (92)
CeeDee Lamb (17) Justin Jefferson (22) Brandon Aiyuk (25)
Here are my Top 10 in my very non-expert, don't pay much attention outside of the Bears and Fantasy Football opinion. Like david said, the top two probably have to be Jefferson and Chase.